cis-diiododiammineplatinum(II)

Basic Properties and Structure   Chemical formula: H₆I₂N₂Pt or cis-[Pt(NH₃)₂I₂]     Molecular weight: approx. 482.95 g/mol     CAS number: 15978-93-5     Appearance: pale yellow to brown solid     Structure: The core is a platinum(II) ion (Pt²⁺) with a squareplanar geometry, coordinated to two ammonia molecules (NH₃) and two iodide ions (I⁻) in a cis arrangement (the two iodide ligands are adjacent to each other).   Main Uses and Applications   Anticancer drug research: As a diiodo analogue of cisplatin, it has itself been studied as a potential anticancer agent. Some reports indicate that it inhibits cancer cell growth by binding to DNA, and antitumor activity has been demonstrated in both in vitro and in vivo experiments.     Chemical synthesis intermediate: It is an important precursor for the synthesis of other platinumbased complexes. For example, it can be used to prepare derivatives of another platinum anticancer drug, carboplatin, or for analytical method development and qua…